Влияние COVID-19 на менструальный цикл
Пандемия COVID-19 по-прежнему остается одной из наиболее актуальных проблем для мирового сообщества. Известно, что у пациентов, перенесших COVID-19, помимо поражения органов дыхательной системы, имеют место осложнения и со стороны других систем органов. За последние 2 года многие женщины отметили впервые возникшие нарушения менструального цикла, что вызывает настороженность в отношении влияния SARS-CoV-2 на женскую репродуктивную функцию, однако на сегодняшний день накоплено недостаточно клинических и статистических данных, позволяющих установить этиологию этих нарушений. Данный обзор посвящен потенциальным причинам расстройств менструального цикла у женщин репродуктивного возраста во время коронавирусной пандемии: возможному прямому влиянию SARS-CoV-2 на органы женской репродуктивной системы, роли цитокинового шторма в нарушении менструального цикла, влиянию длительной терапии глюкокортикостероидами и антикоагулянтными препаратами на расстройство менструальной функции, ассоциации повышенного уровня стресса и тревоги с нарушениями менструального цикла, а также влиянию вакцинации от COVID-19 на женскую репродуктивную функцию. Имеющиеся данные указывают на то, что нарушения менструального цикла с большой вероятностью не являются специфичным проявлением новой коронавирусной инфекции, а скорее, связаны с испытываемым женщинами стрессом, иммунной системной воспалительной реакцией или проводимой терапией.
Ключевые слова: COVID-19, SARS- CoV-2, нарушения менструального цикла.
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