Влияние COVID-19 на менструальный цикл

Демидова Т.Ю., Гурова И.Д., Лобанова К.Г., Короткова Т.Н. Влияние COVID-19 на менструальный цикл. FOCUS Эндокринология. 2022; 1: 67–73. DOI: 10.47407/ef2022.3.1.0060

Demidova T.Yu., Gurova I.D., Lobanova K.G., Korotkova T.N. An impact of COVID-19 on menstrual cycle. FOCUS Endocrinology. 2022; 1: 67–73. DOI: 10.47407/ef2022.3.1.0060

Пандемия COVID-19 по-прежнему остается одной из наиболее актуальных проблем для мирового сообщества. Известно, что у пациентов, перенесших COVID-19, помимо поражения органов дыхательной системы, имеют место осложнения и со стороны других систем органов. За последние 2 года многие женщины отметили впервые возникшие нарушения менструального цикла, что вызывает настороженность в отношении влияния SARS-CoV-2 на женскую репродуктивную функцию, однако на сегодняшний день накоплено недостаточно клинических и статистических данных, позволяющих установить этиологию этих нарушений. Данный обзор посвящен потенциальным причинам расстройств менструального цикла у женщин репродуктивного возраста во время коронавирусной пандемии: возможному прямому влиянию SARS-CoV-2 на органы женской репродуктивной системы, роли цитокинового шторма в нарушении менструального цикла, влиянию длительной терапии глюкокортикостероидами и антикоагулянтными препаратами на расстройство менструальной функции, ассоциации повышенного уровня стресса и тревоги с нарушениями менструального цикла, а также влиянию вакцинации от COVID-19 на женскую репродуктивную функцию. Имеющиеся данные указывают на то, что нарушения менструального цикла с большой вероятностью не являются специфичным проявлением новой коронавирусной инфекции, а скорее, связаны с испытываемым женщинами стрессом, иммунной системной воспалительной реакцией или проводимой терапией.

Ключевые слова: COVID-19, SARS- CoV-2, нарушения менструального цикла.

Демидова Татьяна Юльевна - д-р мед. наук, проф., зав. каф. эндокринологии лечебного факультета ФГАОУ ВО «РНИМУ им. Н.И. Пирогова». E-mail: [email protected]; ORCID: 0000-0001-6385-540X; eLIBRARY.RU SPIN: 9600-9796; Scopus Author ID: 7003771623
Лобанова Кристина Геннадьевна - ассистент, каф. эндокринологии лечебного факультета, ФГAОУ ВО «РНИМУ им. Н.И. Пирогова»
Короткова Татьяна Николаевна - канд. мед. наук, зав. лаб. клинической биохимии, аллергологии и иммунологии, ФГБУН «ФИЦ питания и биотехнологии»
Гурова Ирина Дмитриевна - ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России, Москва, Россия

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